It is a phenomenon that inevitably occurs with aging
Growing aged people
They should work to live longer life
They want to stay healthier and look younger than true age
Modernized lifestyle
01UV Rays
Through our lifetime, we accumulate damage generated by UV radiation.
Naturally occurring UV radiation is the environmental mutagen responsible for the largest percentage of
environmentally induced skin pathologies, inducing erythema and inflammation, degenerative aging changes, and cancer.
Ref. Amaro-Ortiz A et al., Molecules, 2014, 19(5):6202-6219
02Stress
Mechanisms by which stress leads to immune dysfunction, oxidative radicals, and ultimately DNA damage via neuronal,
endocrine, and immune modulation present a possible intervention for skin aging.
Psychological stress can affect the skin. High amounts of cortisol (The stress hormone) can break down the skin’s collagen and elastin, and form wrinkles.
Ref. Dunn JH et al., Dermatol. Online. J., 2013, 19(6):18561
03Nutritional Imbalance
Changes in the physiology of the skin in obesity include:
Altered epidermal barrier leading to increased transepidermal water loss
Impaired collagen production leading to wrinkle formation
Ref. Yosipovitch et al., J. Am. Acad. Dermatol., 2007, 56(6):901-916
04Pollution
Long-term or acute exposure to air pollutants can lead to varying degrees of damage to health, ranging from respiratory diseases to premature death.
It has also been known for some years that air pollutants cause the skin to age prematurely and lead to pigment spot formation.
Ref. Schikowski T et al., Curr. Environ. Health. Rep., 2020, 7(1):58-64
05Lack of Sleep
Poor sleep quality accelerates signs of skin aging and weakens the skin’s ability to repair itself at night.
Good quality sleep was associated with more efficient recovery from UV-induced erythema, and better self-perception of overall appearance.
Ref. Oyetakin-White P et al., Clin. Exp. Dermatol., 2015, 40(1):17-22