BTC Corporation

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Why need DermaNiA?

Aging Society

  • Intrinsic skin aging
    • It is a phenomenon that inevitably occurs with aging
  • Growing aged people
    • They should work to live longer life
    • They want to stay healthier and look younger than true age

Modernized lifestyle

  • 01UV Rays

    • Through our lifetime, we accumulate damage generated by UV radiation.
    • Naturally occurring UV radiation is the environmental mutagen responsible for the largest percentage of environmentally induced skin pathologies, inducing erythema and inflammation, degenerative aging changes, and cancer.

      Ref. Amaro-Ortiz A et al., Molecules, 2014, 19(5):6202-6219

  • 02Stress

    • Mechanisms by which stress leads to immune dysfunction, oxidative radicals, and ultimately DNA damage via neuronal, endocrine, and immune modulation present a possible intervention for skin aging.
    • Psychological stress can affect the skin. High amounts of cortisol (The stress hormone) can break down the skin’s collagen and elastin, and form wrinkles.

      Ref. Dunn JH et al., Dermatol. Online. J., 2013, 19(6):18561

  • 03Nutritional Imbalance

    • Changes in the physiology of the skin in obesity include:
      • Altered epidermal barrier leading to increased
        transepidermal water loss
      • Impaired collagen production leading to wrinkle formation

      Ref. Yosipovitch et al., J. Am. Acad. Dermatol., 2007, 56(6):901-916

  • 04Pollution

    • Long-term or acute exposure to air pollutants can lead to varying degrees of damage to health, ranging from respiratory diseases to premature death.
    • It has also been known for some years that air pollutants cause the skin to age prematurely and lead to pigment spot formation.

      Ref. Schikowski T et al.,
      Curr. Environ. Health. Rep., 2020, 7(1):58-64

  • 05Lack of Sleep

    • Poor sleep quality accelerates signs of skin aging and weakens the skin’s ability to repair itself at night.
    • Good quality sleep was associated with more efficient recovery from UV-induced erythema, and better self-perception of overall appearance.

      Ref. Oyetakin-White P et al.,
      Clin. Exp. Dermatol., 2015, 40(1):17-22